Controlled Data Users
Researchers apply to the ICGC Data Access Compliance Office for access to ICGC controlled data. Every approved project appears on this page.
The ICGC Data Access Compliance Office (DACO) is a centralised governance body that manages controlled access to cancer genomic data on behalf of the international ICGC consortium.
DACO provides a single compliance pathway, consolidating oversight across dozens of institutions and jurisdictions. DACO maintains rigorous ethical, legal, and procedural standards that enable responsible, cross-border data sharing while preserving the confidentiality of research participants, supporting efficient and trusted collaboration in global cancer genomics research.
We publish this list on the principle of transparency, to research participants and the wider community how ICGC data is being used. Approvals run for two years and are assessed against the ICGC Policies and Guidelines. To raise a question about any project listed here, contact DACO.
Approved applications in 2026, current as of September 1, 2026.
Taipei Medical University
Clinical Utility of A to I RNA editing landscapes in pediatric and adult brain tumours
Cancer Hospital, Chinese Academy of Medical Sciences
CCA genome mutation research
Indian Institute of Science
Investigating the role of epigenetic alterations in oral cancer stemness and drug resistance
Computational Characterisation of HRD related Molecular and Microenvironmental Features in Pancreatic Ductal Adenocarcinoma
Bioinformatics discovery of robust melanoma biomarkers for tumour boundary delineation using ICGC controlled multi-omics data
Identification of unique variant signature in GEP-NETs and its multiomics interpretation
Hospital Puerta de Hierro
Anti-HER2 and anti-B7H targeted adoptive cell therapies for gastrointestinal cancer
The role of A to I editing on cancer development and progression
Development and validation of proprietary algorithm for the classification of somatic variants according to the 2017 AMP/ASCO/CAP guidelines
Analysis of driver mutations in cancer
University of Applied Sciences, Northwestern Switzerland
Pan cancer re-analysis of cancer specific transcript expression
A cancer whole genome comparison of early and late onset tumours
Impact of germline DNA repair gene variants on somatic mutational signatures across human cancers
Landscape of somatic mutagenesis and selection in cancer
VIB
Non-invasive liquid biopsy assay development for CUP based on cfDNA methylation
Determinants of response to BTK degraders in chronic lymphocytic leukaemia
Identifying cancer drivers through integrated analysis of coding and non-coding mutations in molecular and systems contexts
Optimizing phylogeny tools for clinical utility
Exploring the relationship between somatic mutations and non B DNA in cancers
Decoding the ALT pathway: Identifying synthetic lethal targets and biomarkers for precision cancer therapy
Dresden University of Technology
Self supervised foundation models for large scale cancer genome analysis
Tianjin Medical University
Pan cancer analysis of functional somatic mutations in non-coding RNA loci and their regulatory impact
Research Institute of Molecular Pathology
Prevalence and genomic context of deletion associated vulnerabilities in cancer
Characterising Gene Content on ecDNA in HER2 positive breast cancer using whole genome sequencing
Esophageal adenocarcinoma based on gene fusion events
Cross indication biomarkers transfer learning to predict therapeutic response
Role of AN09 expression in epithelial-mesenchymal transition and distant metastases in pancreatic ductal adenocarcinoma
Tumourigenic scoring of cancer patient derived organoids
Molecular defects in gynaecological cancers: Genomic correlations and phenotypic consequences
Independent external validation of biomarker probability fusion across ICGC cancer Cohorts
University Health Network
Genome-wide DNA methylation profiling of follicular lymphoma to inform cell-free DNA biomarker development
Genome specificity of mutagenesis
Leveraging genomic variation to understand mutational processes shaping cancer genomics
Longitudinal clinico-genomic analysis of treatment response and resistance in cancer
Somatic copy number heterogeneity and structural variants as drivers of tumour progression in clear cell renal cell carcinoma
Fred Hutchinson Cancer Centre
Epigenetics and risk prediction for esophageal adenocarcinoma
Understanding the inherited and acquired genetic changes that influence development of cancers (including myelodysplastic syndrome and acute myeloid leukaemia)
Massachusetts General Hospital
Homologous recombination deficiency in localised prostate cancer
Indian Institute of Technology
Identifying the key mutational drivers of therapy resistance in cancer
Dana Farber Cancer Institute
Prostate cancer subtype identification
Integrative analysis of chromatin context and somatic mutation patterns to infer cancer cell of origin
The microenvironment contributions to cancer stemness and therapy resistance in esophagogastric adenocarcinoma
Nationwide Children's Hospital
Meta-analysis, validation and development of osteosarcoma patient stratification methodologies
Validation of single-cell-derived transcriptional tumour states associated with chemotherapy response in oesophageal adenocarcinoma
Systemic mutational processes and genetic determinants of internal and skin cancer risk in xeroderma pigmentosum
The Children's Hospital of Philadelphia
The stability of epigenetic cell identity in cancer
Yonsei University College of Medicine
Analysis of circulating nucleic acid genetic profiles in lymphoma patients
Validation of a Novel Transcriptomic Signature for Metastatic Risk in LIRI-JP liver cancer
Evaluating RNA foundation model representations for prognostic biomarker discovery and survival prediction across ICGC ARGO and ICGC 25k Oncology cohorts
Pan-Cancer Analysis of the relationship between G-Quadruplex Structures and Somatic Mutations
Centre for Excellence in Molecular Cell Science
Dissecting Genetic Variation Effects on RNA Regulation Across Cancers
Integrative analysis of transcriptomic markers and histological features in hepatocellular carcinoma
University College London
Developing TCR-T immunotherapy for the treatment of Ewing Sarcoma
Universidad Autonoma de Nuevo León
Genomic Landscape and determinants of somatic mitochondrial DNA integration across human cancers
Immune Subtyping of Pancreatic Ductal Adenocarcinoma Using TCGA-PAAD Transcriptomic Data, with an Exploratory Neoantigen Prioritisation Module
Mapping Cancer-Type-Specific Noncoding Mutation Hot Regions Through 3D Genome Architecture and the Epigenome
The University of Texas MD Anderson Cancer Center
Biliary Tract Cancer RNAseq Analysis
University of the Basque Country (UPV/EHU)
Molecular advances in the classification and prognosis of pediatric medulloblastoma by integrating transcriptomic and genomic data
Centre de Recherche du CHUM
Circulating nucleic acid sequencing for the detection of head and neck cancer
Investigating Presence of HCMV in Pediatric Medulloblastoma Through Multi-Omic Sequencing Analysis
Indian Institute of Technology Kharagpur
Canada's Michael Smith Genome Sciences Centre, a program of the Provincial Health Services Authority
The Canadian Genomic Data Commons
TERT promoter SNP project
Queen Mary University of London
Analysis of sequencing data for Barrett's Oesophagus and Oesophageal Adenocarcinoma cell lines
Biomarker analysis of solid tumors
Deciphering the molecular, phenotypic and functional landscapes of sarcomas
Samsung Precision Genome Medicine Institute
Genomic and transcriptomic landscape of biliary tract cancer
All India Institute of Medical Sciences
Integrating Spatial Transcriptomics and WES to Identify Biomarkers for Oral Cancer Progression
Genome-wide somatic variant analysis to identify CRISPR targets for cancer-selective cell killing
Integrative Multi-Omic Modeling of Platinum Resistance and Clonal Evolution in Advanced Solid Tumors
Discovery of Tissue-of-Origin Markers in Cancer
Evaluation of Computational Methods for Somatic Variant Detection and Genomic Instability in Paired Tumor/Normal Whole-Genome Sequences
External Validation and Reference Characterization of DNA Methylation at Defined CpG Loci Distinguishing Chronic Lymphocytic Leukemia from Myeloid Leukemias
Integrated analysis of genomic and transcriptomic profiles to examine CD73/NT5E as a driver of drug-resistance and immunosuppression in biliary cancer
Validation of gene expression signatures associated with cancer agrressiveness
Humanitas Research Hospital - Humanitas Mirasole S.p.A.
Whole-genome sequencing redefines ampullary carcinoma as anatomical disease
Hypoxia gene signature as a promising biomarker to improve pancreatic cancer patient management
Center for Cancer Research, National Cancer Institute
Using Genomic Data to Improve Understanding of Liver Cancer and Personalize Treatment Approaches
Integrative Pan-Cancer Multi-Omics Characterization within the Cancer Data Maps Harmonized Resource
Predictive Modeling of Therapeutic Response and Acquired Resistance Using Longitudinal Multi-Omic Data
Immunospuressive Microenvironment and PI3K/mTOR Activation in Leiomyosarcoma
Impact of Lifestyle-Related Factors on the Landscape of Driver Alterations in Gastrointestinal Malignancies
Sun Yat-sen University Cancer Center
Integrative Genomic and Immune Landscape Analysis of Colorectal Cancer Subtypes
Seoul National University
Genomic Characterization of Telomere Maintenance Mechanisms in Pancreatic Neuroendocrine Tumors
Nanjing Medical University
China
Molecular and Clinical Determinants of Treatment Response Heterogeneity in Pancreatic Cancer: A Multi-omics and Causal Inference Analysis Based on ICGC ARGO Cohort
University of Science and Technology of China (USTC)
Artificial Intelligence for Multimodal Analysis of Colorectal Cancer
Fundació Privada per a la Recerca i la Docència Sant Joan de Déu
Mechanical RNA Splicing Defects in Pediatric Cancer: characterization and identification of novel therapeutic targets
Sun Yat-sen University Cancer Center
Spatial Immune Heterogeneity and Tumor Evolution in Primary Liver Cancer: A Multi-omics Data Integration Study
Instituto de Química, Universidade de São Paulo
Establishment of functional genomics platforms for discovery of molecular markers and therapeutical targets in pancreatic cancer and melanoma